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Explore every story, insight, and deep dive from the Horizon archive.

Protein2026-08-16

From Wound Healing to Vascular Remodeling: Why EGF, FGF2, and VEGF121 Are Essential Tools in Growth Factor Research

Growth factors are the molecular architects of tissue development, repair, and homeostasis. They orchestrate cell proliferation, differentiation, migration, and survival through precisely regulated signalling cascades that have profound implications for both health and disease. Among the dozens of growth factors that have been characterised,EGF,FGF2, andVEGF121stand out as three of the most extensively studied and translationally relevant members of this family. Each governs a distinct biologica

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Protein2026-08-14

From Inflammation to Apoptosis: Why IL6R, VEGFA, and TNFRSF10B Are Reshaping Cytokine and Growth Factor Receptor Research

The cytokine and growth factor receptor landscape has long been defined by a handful of well-characterised pathways—each with its own established inhibitors and clinical applications. But the most compelling developments in this space are increasingly coming from targets that bridge multiple biological processes: receptors that link inflammation to angiogenesis, growth factors that drive both tumour vascularisation and immune evasion, and death receptors that are finally realising their potentia

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Protein2026-08-13

Beyond the Usual Suspects: Why HER3, EGFR, and CD2 Are Reshaping the Oncology Target Landscape

The oncology target landscape has long been dominated by a handful of well‑characterised molecules—HER2, PD‑1, CD19—each with their own blockbuster drugs and established clinical pathways. But the most exciting developments in precision oncology are increasingly coming from targets that sit slightly off‑centre: receptors that were once considered "undruggable," co‑stimulatory molecules that were overlooked, and signalling nodes that only revealed their true importance when resistance to existing

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Protein2026-08-12

From pp28 to Spike: Why CMV and Coronavirus Targets Are Driving the Next Wave of Antiviral Research

In the post‑pandemic era, the urgency of antiviral research has never been clearer. While emerging viruses capture headlines, persistent pathogens like cytomegalovirus (CMV) continue to impose a heavy burden on immunocompromised patients, transplant recipients, and newborns worldwide. The common thread connecting these seemingly disparate threats is the critical role of viral structural proteins—both as targets for therapeutic intervention and as tools for understanding host‑pathogen dynamics.Am

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